Fighting off Depression After MDMA & Methamphetamine
MDMA, also called Molly and Ecstasy, is a drug that achieves its psychedelic and stimulating effects by increasing the activity of neurotransmitters in the brain—including Dopamine and Serotonin. Dopamine and Serotonin are two neurotransmitters that play critical roles in regulating mood and emotions. When a person ingests MDMA, the increase in these neurotransmitters causes the initial “high.” However, as the drug wears off, the activity of the neurotransmitters decreases, and the deficit results in a “low,” often resulting in depression, anxiety, sleep disturbance, and irritability. Extended use of MDMA can cause the brain to adapt to the increased activity of these neurotransmitters, causing the subsequent “low” to become more significant given the brain’s desensitization to the brain’s naturally occurring Dopamine and Serotonin.